Vitamin Analysis

Adamson Analytical Laboratory’s Dietary Supplement Lab has the utmost capability on testing vitamin actives in raw materials, tablets, capsules, solutions, or powder mixes in the form of proteins such as milks or soy matrices. The test analyses are performed using state-of-the-art instruments such as HPLC (high performance liquid chromatography), and GC (gas chromatography).

There are two main class of  vitamins: water soluble vitamins and fat (oil) soluble vitamins. Adamson’s test vitamin raw materials and finished products using official USP methods under the USP Dietary Supplement Chapter and other published validated methods such as AOAC, etc.

For regulatory compliance according to 2007 DSHEA, all vitamin raw materials used in supplements and food products must be tested for identity by infrared spectrometer and assay for potency percentage. The manufacturer must assure the quality and purity of each raw material before use in production. Adamson’s Nutrition Lab has tabulated a table summary of USP vitamin specifications on individual raw materials.

The vitamin‘s finished product can be in the form of capsules, tablets, powder mixes or oral liquid solutions.

The USP (United States Pharmacopeia) has set acceptable allowable ranges based on individual active label claims for vitamins in finished products. Vitamin potency that is less than minimum range in the finished product is called sub-potency. Based on GMP regulation, if the sample fails the specification it must be rejected and disposed of properly, and under no circumstances be sold to consumers.

The Dietary Reference Intake (DRI) table published from the Institute of Medicine (IOM) and National Academy of Science provides a guideline to dietary supplement manufacturers on vitamin and miniral daily dosages.

Nutrient Milligram/Microgram
Ascorbic Acid 60 mg
Vitamin D 400 IU
Vitamin E 30 IU
Vitamin K 80 IU
Thiamine Vitamin B1 1.5mg
Riboflavin Vitamin B2 1.7 mg
Niacin Vitamin B3 20 mg
Pyridoxine Vitamin B6 2 mg
Folic Acid Vitamin B9 400 µg
Cyanocobalamine B12 6 µg
Biotin Vitamin B7 300 µg
Pantothenic Acid Vit B5 10 mg
Vitamin A 5000 IU


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